The Truth Behind Memory Loss With Age

What Is Memory Loss With Age?

Senior citizens experience mild forgetfulness from time to time. This is normal. What’s not normal is forgetting where you are, the time of day or season of the year, important past or future events, or how to carry out everyday tasks. These are all signs of memory loss with age and other underlying problems affecting brain cells and their capacity to store or recall memories. Some other telltale signs are having trouble learning new things or using words correctly, as well as suddenly changing mood or behavior.

What Causes Age-Related Memory Loss?

Healthy brain cells, neural connections and plasticity (ability to form new or reorganize connections between brain cells), and proper communication between brain cells are necessary for healthy memory function. The following factors can interfere with these processes and lead to quicker age-related memory decline:

  • Head injury or brain trauma
  • Chronic stress
  • Brain infection
  • Certain medications
  • Brain disorders, such as Alzheimer’s disease and dementia
  • Medical condition such as thyroid disorder
  • Vitamin deficiency such as B12 deficiency
  • Severe drug or alcohol abuse

Alzheimer’s disease destroys brain cells (i.e., neurons) and their connections in specific parts of the brain first like the hippocampus (responsible for memory storage) and a small portion of the cortex (where most short-term, working memories reside), prior to spread in the entire cerebral cortex responsible for speech, reasoning and behavior, and ultimately across our brain. The memory loss with age is due to the four main following mechanisms:

Amyloid-Beta Plaques

A protein fragment known as amyloid-beta plays a significant role in the development of Alzheimer’s disease, a condition marked by progressive memory loss in the elderly. For more than 25 years, scientists thought that the root cause of Alzheimer’s disease was due to an accumulation of amyloid-beta fragments outside and between brain cells. Amyloid-beta fragments are very sticky and form a build-up overtime called plaques. These structures are toxic for neurons and prevent proper cell-cell communication and connections resulting in altered function.

Neurofibrillary Tangles

Neurofibrillary tangles are twisted strands of another protein called Tau that accumulates inside neurons. Tangles prevent neurons from functioning and communicating properly and also contribute to brain cell death and memory loss with age. In normal conditions, Tau protein binds to structures (called microtubules) responsible for neurons’nutrients transport system.  In disease conditions, Tau protein becomes abnormal and is no longer attached to microtubules, thus altering nutrients and waste flow in and out of brain cells. With poor cell function and communication with other neurons,  cells gradually die.


A growing set of evidence has shown that inflammation is also a major contributor to Alzheimer’s and other neurodegenerative diseases. A recent large, longitudinal study demonstrated that Chronic inflammation in middle age individuals can cause quicker cognitive decline later on in life. In some instances, amyloid-beta, itself, may activate immune cells and trigger an inflammatory response that destroys cells and brain tissue. Natural memory supplements usually contain antioxidants and anti-inflammatory compounds that work to get rid of toxins in the body that cause oxidative damage.

Vascular Changes

In the aging brain, blood vessels change in structure that may lead to a breakdown of the blood-brain barrier that protects our brain against harmful agents. In addition, amyloid-beta deposits in brain arteries may affect blood flow and oxygen levels to the brain. Because of these issues, the brain becomes less effective at getting rid of waste and used materials. It could then trigger an inflammatory response that could lead to chronic issues encounter in people with Alzheimer’s disease.

General Cellular Dysfunctions

Mitochondria are cell components responsible for converting food into energy for cells and for communication between cells. Neurons require a large number of functional mitochondria to transmit signals to other brain cells in brain areas responsible for memory. With age, mitochondria become less effective and less numerous resulting in decreased communication between neurons and memory issues. A reduction in these cell-cell communications leads to oxidative stress that is detrimental to neurons. In addition, other external factors like malnutrition, chronic stress, medication, and brain injury could contribute to an increase in oxidative stress and cell dysfunction. Those cellular events contribute to memory deficit and cognitive decline.

Supplements for memory are designed to promote brain cell repair, increase blood flow and reduce oxidative stress and inflammation. Inflawell Memory Support supplement, for example, contains the active ingredients Boswellia serrata and Bacopa monnieri. Several clinical studies concluded that the two plant extracts can safely reduce inflammation and improve memory and cognitive function.

Inflawell™ Supplement for Memory

Although memory loss with age is common, a natural health supplement for memory health, such as Inflawell Memory Support by Kondor Pharma, could be a premium choice to help slow down brain aging and age-related memory loss.

Inflawell™ by Kondor Pharma is an approved natural health supplement that helps support brain function and memory. Read more about this product on our website or call 800-892-6981 for more information.

Related Posts

Scroll to Top