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Clinical Research

Let the data speak for itself

We prioritize clinical research so that you can rest assured our products are efficacious at the recommended dose.

Clinical trials—that is, randomized, placebo-controlled experiments involving human participants—are key for verifying whether a product has the intended effect claimed on the label.

Results from our in-house clinical trial on the core ingredient in our formulations, boswellia, are outlined below along with additional supporting research for the other ingredients contained in our products.

Supporting human research and health benefits of our ingredients

Clinical trial with our boswellia serrata extract

We tested a standardized extract of Boswellia serrata in a randomized, double-blind, placebo-controlled clinical study on 85 patients with mild to moderate Alzheimer’s Disease.

Boswellia showed improvement of memory and reduction of blood markers of inflammation (specifically pro-inflammatory and anti-inflammatory cytokines) after 6 months of treatment.

This graph is a summarized depiction of the results.

Bacopa monnieri

A recent, randomized, double-blind placebo-controlled clinical study on 60 healthy elderly subjects (mean age 62.6 years) received either a standardized extract of Bacopa monnieri or placebo once daily for 12 weeks. Results showed that the Bacopa monnieri extract improves attention, brain function, and memory[1].

Similarly, another randomized, double-blind placebo-controlled clinical study on 48 healthy elderly volunteers (mean age 73.5 years) showed that a treatment of 12 weeks with Bacopa monnieri safely improve memory and cognitive tasks[2].

  • Helps support cognitive health and/or brain function*
  • Helps support memory*

* According to Health Canada regulations

[1] Peth-Nui et al. Hindawi publishing corporation. Evidence-based complementary and alternative medicine (2012) 1-10.

[2] Calabrese et al. Journal of alternative and complementary medicine. Vol. 14 (6)(2008) 707-713.

Vitamin D

Human studies strongly support a correlation between deficiency in Vitamin D and risks of cognitive impairment or dementia in aging populations. Vitamin D imbalance has also an effect on inflammation, immune system and oxidative stress[1]. Overall, vitamin D:

  • Helps (to) maintain/support immune function*
  • Helps with immune function*
  • Helps to prevent vitamin D deficiency*

[1] Landel et al. Journal of Alzheimer’s Disease. Vol 53 (2016) 419–444

* According to Health Canada regulations

Panax ginseng

Panax ginseng is a common herb used in Chinese medicine. In Japan, Korea and China, roots, leaves and stems have been used for centuries to treat diseases associated with inflammation, oxidative stress and brain cell damage. Ginsenosides are the main active substances found in Ginseng extracts. One clinical study on people who suffered from ischemic stroke showed that ginsenosides improve the outcomes of patients on the National Institutes of Health Stroke Scale (NIHSS) following 14-day treatment compared with baseline taken within 12 hours of hospital admission[1]. The NIHSS is an assessment tool that can determine the extent of damage and monitor recovery after stroke.

[1] Liu et al., Eur J Neurol. (2009) 16(5) 569-75.

Vitamin C

Vitamin C is an essential micronutrient for humans, with a variety of benefits. Vitamin C contributes to immune defense by supporting various functions of the immune system[1]. It is also a potent antioxidant and a molecule essential for maintaining good general health.

[1] Carr AC and Maggini S., Nutrients. (2017) 9(11) 1211

Lutein

Lutein is a purified extract prepared from the petals of marigold flowers. Lutein is a type of carotenoid with antioxidant properties that is accumulated mainly in the eye and known to play a crucial role in optimizing vision in healthy individuals. In addition to its benefit for the vision, it has also been shown to provide antioxidant and brain health benefits[1].

[1] Stringham JM et al., Current Developments in Nutrition. (2019) 3(7): nzz066.

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